{"product_id":"bmp-5-l163-polyclonal-antibody-bs3455","title":"BMP-5 (L163) Polyclonal Antibody-BS3455","description":"\u003cp\u003eBMP-5 (L163) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS3455-50, BS3455-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P22003\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1:2000~1:5000\u003c\/p\u003e\n\n\u003cp\u003eBackground: Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including cartilage and bone formation or neurogenesis.Initiates the canonical BMP signaling cascade by associating with type I receptor BMPR1A and type II receptor BMPR2.In turn, BMPR1A propagates signal by phosphorylating SMAD1\/5\/8 that travel to the nucleus and act as activators and repressors of transcription of target genes.Can also signal through non-canonical pathway such as MAPK p38 signaling cascade to promote chondrogenic differentiation.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: BMP-5 (L163) polyclonal antibody detects endogenous levels of BMP-5 protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of BMP-5 (L163)polyclonal antibody at 1:2000 dilution\u003cbr\u003e\nLane1:EC9706 whole cell lysate(30ug)\u003cbr\u003e\nLane2:HCT116 whole cell lysate(30ug)\u003cbr\u003e\nLane3:A549 whole cell lysate(30ug)\u003cbr\u003e\nLane4:HEK293T whole cell lysate(30ug)\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 53 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Bone morphogenetic protein 5; BMP-5\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to Human BMP-5.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42908706406579,"sku":"BS3455-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42908706439347,"sku":"BS3455-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_336c2008-be5a-4f4f-a0e8-14618e4290f8.jpg?v=1703006066","url":"https:\/\/afsbio.com\/products\/bmp-5-l163-polyclonal-antibody-bs3455","provider":"AFSBio Inc.","version":"1.0","type":"link"}