{"product_id":"bmp2-monoclonal-antibody-e-ab-70352","title":"BMP2 Monoclonal Antibody - E-AB-70352","description":"\u003cp\u003eBMP2 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-70352-60, E-AB-70352-120, E-AB-70352-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: BMP2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: BDA2; BMP-2; BMP-2A; Bmp2; BMP2; BMP2A; Bone morphogenetic protein 2; Bone morphogenetic protein 2A\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cardiovascular, Signal Transduction, Stem Cells\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone No.: 2H6D12\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P12643,P21274,P49001\u003c\/p\u003e\n\n\u003cp\u003eBackground: Bone morphogenetic protein-2 (BMP-2) is a member of the transforming growth factor-beta (TGFB) superfamily. BMP2 is synthesized as a 60 kDa precursor that is processed in the secretory pathway to a small 18 kDa monomer; 2 monomers then associate to form the active 30 kDa homodimer, which binds to its receptor. There is also a 40-45 kDa form of BMP2, as an amino-terminal propeptide. BMP2 can induce bone formation and regeneration during early embryonic development. It is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 2.65 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein corresponding to  Mouse BMP2\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:200-1:800\u003c\/p\u003e\n\n \n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43135932694707,"sku":"E-AB-70352-60","price":224.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43135932727475,"sku":"E-AB-70352-120","price":364.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43135932760243,"sku":"E-AB-70352-200","price":574.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_74c122e3-f091-48eb-a530-56a585f8ff61.png?v=1709986710","url":"https:\/\/afsbio.com\/products\/bmp2-monoclonal-antibody-e-ab-70352","provider":"AFSBio Inc.","version":"1.0","type":"link"}