{"product_id":"bmx-phospho-y566-polyclonal-antibody-bs64517","title":"BMX (Phospho-Y566) Polyclonal Antibody-BS64517","description":"\u003cp\u003eBMX (Phospho-Y566) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS64517-50, BS64517-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P51813\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, IF\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB:1:500~1:1000 IHC:1:50~1:200 IF:1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: ETK, also known as BMX, is a member of the Bruton's tyrosine kinase (Btk) family. It is expressed in a variety of hematopoietic, epithelial and endothelial cells. Etk, like other Btk family members, contains a pleckstrin homology (PH) domain and Src homology SH3 and SH2 domains. It participates in multiple signal transduction pathways. Phosphorylation of Tyr566 by Src kinase is required for activation of Etk in vivo. In endothelial and epithelial cells, Etk is regulated by FAK through phosphorylation at Tyr40.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: BMX (Phospho-Y566) polyclonal antibody detects endogenous levels of BMX protein only when phosphorylated at Tyr566.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 78 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of BMX (Phospho-Y566) polyclonal antibody at 1:500 dilution\u003cbr\u003e\nLane A: HEK293T whole cell lysate\u003cbr\u003e\nLane B: Hela whole cell lysate\u003cbr\u003e\nLane C: The Kidney tissue lysate of Mouse\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Cytoplasmic tyrosine-protein kinase BMX; Bone marrow tyrosine kinase gene in chromosome X protein; Epithelial and endothelial tyrosine kinase; NTK38; BMX\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic phosphopeptide derived from human BMX around the phosphorylation site of Tyrosine 566.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Phosphorylation\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":43044027367603,"sku":"BS64517-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":43044027400371,"sku":"BS64517-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_99f2f586-95b0-4370-bf4c-acd5ca1ea768.jpg?v=1707738651","url":"https:\/\/afsbio.com\/products\/bmx-phospho-y566-polyclonal-antibody-bs64517","provider":"AFSBio Inc.","version":"1.0","type":"link"}