{"product_id":"bmx-polyclonal-antibody-ra22454","title":"Bmx Polyclonal Antibody - RA22454","description":"\u003cp\u003eBmx Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA22454-50, RA22454-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: BMX non-receptor tyrosine kinase (BMX) Homo sapiens This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. Immunofluorescence: 1\/200 - 1\/1000. ELISA: 1\/5000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: BMX; Cytoplasmic tyrosine-protein kinase BMX; Bone marrow tyrosine kinase gene in chromosome X protein; Epithelial and endothelial tyrosine kinase; ETK; NTK38\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC-p; IF\/ICC; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 660\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 78\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P51813\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121112047795,"sku":"RA22454-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121112080563,"sku":"RA22454-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_5863a5d3-7ad5-4017-858c-b834b46feed9.png?v=1773371269","url":"https:\/\/afsbio.com\/products\/bmx-polyclonal-antibody-ra22454","provider":"AFSBio Inc.","version":"1.0","type":"link"}