{"product_id":"bnp-monoclonal-antibody-bt-mca0230","title":"BNP Monoclonal Antibody - BT-MCA0230","description":"\u003cp\u003eBNP Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA0230-50, BT-MCA0230-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cardiovascular; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: NPPB\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Natriuretic peptides B\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P16860; Mouse: P40753\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: NPPB; Natriuretic peptides B; Gamma-brain natriuretic peptide\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 4879\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238670033075,"sku":"BT-MCA0230-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238670065843,"sku":"BT-MCA0230-100","price":420.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_3a3a6e97-d72a-4757-be66-bf58220e33fe.png?v=1769383618","url":"https:\/\/afsbio.com\/products\/bnp-monoclonal-antibody-bt-mca0230","provider":"AFSBio Inc.","version":"1.0","type":"link"}