{"product_id":"bombesin-receptor-2-polyclonal-antibody-ra22467","title":"Bombesin Receptor 2 Polyclonal Antibody - RA22467","description":"\u003cp\u003eBombesin Receptor 2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA22467-50, RA22467-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.\u003c\/p\u003e \n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/40000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC-p; IF (paraffin section)\u003c\/p\u003e \n\n\u003cp\u003eSpecies Cross-Reactivity: Rat; Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 2925\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 50-70\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45119079973043,"sku":"RA22467-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45119080005811,"sku":"RA22467-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_fc06ac0a-cb8c-4a43-b22d-ed0acdaf844a.png?v=1773350842","url":"https:\/\/afsbio.com\/products\/bombesin-receptor-2-polyclonal-antibody-ra22467","provider":"AFSBio Inc.","version":"1.0","type":"link"}