{"product_id":"bradykinin-b1-r-polyclonal-antibody-bt-ap00963","title":"Bradykinin B1 R Polyclonal Antibody - BT-AP00963","description":"\u003cp\u003eBradykinin B1 R Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP00963-20, BT-AP00963-50, BT-AP00963-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by BDKRB1 (bradykinin receptor B1) is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for BDKRB1.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: BDKRB1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Bradykinin B1 R Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 40495\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P46663; Mouse: Q61125\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: BDKRB1; BRADYB1; B1 bradykinin receptor; B1R; BK-1 receptor\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 623\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240141480115,"sku":"BT-AP00963-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240141512883,"sku":"BT-AP00963-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240141545651,"sku":"BT-AP00963-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_9b0eeec4-1846-41cd-b84e-31ab8f110893.png?v=1769404082","url":"https:\/\/afsbio.com\/products\/bradykinin-b1-r-polyclonal-antibody-bt-ap00963","provider":"AFSBio Inc.","version":"1.0","type":"link"}