{"product_id":"braf-polyclonal-antibody-e-ab-66397","title":"BRAF Polyclonal Antibody - E-AB-66397","description":"\u003cp\u003eBRAF Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-66397-60, E-AB-66397-120, E-AB-66397-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: BRAF\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: BRAF; B-RAF1; B-raf; BRAF1; NS7; RAFB1\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer,Cell Biology,Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P15056\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a protein belonging to the raf\/mil family of serine\/threonine protein kinases. This protein plays a role in regulating the MAP kinase\/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human BRAF\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000, IHC 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 84kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 105kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146415243443,"sku":"E-AB-66397-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146415276211,"sku":"E-AB-66397-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146415308979,"sku":"E-AB-66397-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_25c56113-5b75-4092-86af-6967c015c1f6.png?v=1710295181","url":"https:\/\/afsbio.com\/products\/braf-polyclonal-antibody-e-ab-66397","provider":"AFSBio Inc.","version":"1.0","type":"link"}