{"product_id":"brd2-polyclonal-antibody-bt-ap06831","title":"BRD2 Polyclonal Antibody - BT-AP06831","description":"\u003cp\u003eBRD2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP06831-20, BT-AP06831-50, BT-AP06831-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cell biology; Epigenetics and nuclear signaling; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: BRD2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Bromodomain-containing protein 2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P25440; Mouse: Q7JJ13; Rat: Q6MGA9\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Bromodomain-containing protein 2;O27.1.1;Really interesting new gene 3 protein\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 6046\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239068983475,"sku":"BT-AP06831-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239069016243,"sku":"BT-AP06831-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239069049011,"sku":"BT-AP06831-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_5af9aebf-f41d-470c-9ec7-f8a866d96905.png?v=1769388691","url":"https:\/\/afsbio.com\/products\/brd2-polyclonal-antibody-bt-ap06831","provider":"AFSBio Inc.","version":"1.0","type":"link"}