{"product_id":"bre-polyclonal-antibody-ra22486","title":"BRE Polyclonal Antibody - RA22486","description":"\u003cp\u003eBRE Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA22486-50, RA22486-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: brain and reproductive organ-expressed (TNFRSF1A modulator) (BRE) Homo sapiens This gene encodes an anti-apoptotic, death receptor-associated protein that interacts with tumor necrosis factor-receptor-1. The encoded protein acts as an adapter in several protein complexes, including the BRCA1-A complex and the BRISC complex. The BRCA1-A complex possesses ubiquitinase activity and targets sites of double strand DNA breaks, while the BRISC complex exhibits deubiquitinase activity and is involved in mitotic spindle assembly. This gene is upregulated in several types of cancer. [provided by RefSeq, Jun 2016],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: BRE; BRCC45; BRCA1-A complex subunit BRE; BRCA1\/BRCA2-containing complex subunit 45; Brain and reproductive organ-expressed protein\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 9577\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 47\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q9NXR7\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121113358515,"sku":"RA22486-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121113391283,"sku":"RA22486-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_36b3ab29-4baf-4336-86ab-40085b327c1a.png?v=1773371301","url":"https:\/\/afsbio.com\/products\/bre-polyclonal-antibody-ra22486","provider":"AFSBio Inc.","version":"1.0","type":"link"}