{"product_id":"brms-1-polyclonal-antibody-bt-ap00979","title":"BRMS-1 Polyclonal Antibody - BT-AP00979","description":"\u003cp\u003eBRMS-1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP00979-20, BT-AP00979-50, BT-AP00979-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: BRMS1 reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. Breast cancer metastasis-suppressor 1 encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: BRMS1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: BRMS-1 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 28461\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9HCU9; Mouse: Q99N20; Rat: Q5M7T3\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: BRMS1; Breast cancer metastasis-suppressor 1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 25855; Mouse: 107392; Rat: 100911841\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240142889139,"sku":"BT-AP00979-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240142921907,"sku":"BT-AP00979-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240142954675,"sku":"BT-AP00979-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_dede26cb-437e-40c0-8416-4dde0faddc0e.png?v=1769404106","url":"https:\/\/afsbio.com\/products\/brms-1-polyclonal-antibody-bt-ap00979","provider":"AFSBio Inc.","version":"1.0","type":"link"}