{"product_id":"brms-1-polyclonal-antibody-ra22493","title":"BRMS-1 Polyclonal Antibody - RA22493","description":"\u003cp\u003eBRMS-1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA22493-50, RA22493-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: breast cancer metastasis suppressor 1 (BRMS1) Homo sapiens This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC) . The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/20000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: BRMS1; Breast cancer metastasis-suppressor 1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC-p; IF (paraffin section) ; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 25855\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 28\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q9HCU9\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121113751731,"sku":"RA22493-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121113784499,"sku":"RA22493-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_8ed919d1-562c-441e-89aa-10aff4c59cd3.png?v=1773371311","url":"https:\/\/afsbio.com\/products\/brms-1-polyclonal-antibody-ra22493","provider":"AFSBio Inc.","version":"1.0","type":"link"}