{"product_id":"brwd1-polyclonal-antibody-e-ab-64293","title":"BRWD1 Polyclonal Antibody - E-AB-64293","description":"\u003cp\u003eBRWD1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-64293-60, E-AB-64293-120, E-AB-64293-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: BRWD1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: BRWD1; C21orf107; DCAF19; N143; WDR9\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q9NSI6\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) residues which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates multiple transcript variants encoding distinct isoforms. In mouse, this gene encodes a nuclear protein that has a polyglutamine-containing region that functions as a transcriptional activation domain which may regulate chromatin remodelling and associates with a component of the SWI\/SNF chromatin remodelling complex.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human BRWD1 (NP_001007247.1).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:1000-1:3000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 13kDa\/248kDa\/257kDa\/262kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 263kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146318708915,"sku":"E-AB-64293-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146318741683,"sku":"E-AB-64293-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146318774451,"sku":"E-AB-64293-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_c1ac4b1d-967e-4fa1-bc67-644b052db826.png?v=1710293562","url":"https:\/\/afsbio.com\/products\/brwd1-polyclonal-antibody-e-ab-64293","provider":"AFSBio Inc.","version":"1.0","type":"link"}