{"product_id":"btbd1-rabbit-polyclonal-antibody-es17946","title":"BTBD1 Rabbit Polyclonal Antibody - ES17946","description":"\u003cp\u003eBTBD1 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES17946-50, ES17946-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: The C-terminus of the protein encoded by this gene binds topoisomerase I. The N-terminus contains a proline-rich region and a BTB\/POZ domain (broad-complex, Tramtrack and bric a brac\/Pox virus and Zinc finger), both of which are typically involved in protein-protein interactions. Subcellularly, the protein localizes to cytoplasmic bodies. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human BTBD1 AA range: 115-165\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: BTBD1\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: This antibody detects endogenous levels of BTBD1 at Human\/Mouse\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1：500-2000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Ubiquitous, highest levels in testes, heart and skeletal muscle,\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 53kD\u003c\/p\u003e\n\n\u003cp\u003eFunction: Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data\u003cbr\u003e\nFunction: Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins\u003cbr\u003e\nPathway: Protein modification, protein ubiquitination\u003cbr\u003e\nSimilarity: Contains 1 BTB (POZ) domain\u003cbr\u003e\nSubcellular Location: Cytoplasmic bodies\u003cbr\u003e\nSubunit: Interacts with topoisomerase 1 and with TRIM5 isoform Delta. Interacts with CUL3\u003cbr\u003e\nTissue Specificity: Ubiquitous, higher levels in heart and skeletal muscle\u003c\/p\u003e\n\n\n\u003cp\u003eSubcellular Location: Cytoplasm Localizes to punctate or elongated cytoplasmic bodies\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: BTBD1 C15orf1 NS5ATP8\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: BTBD1\u003c\/p\u003e\n\n\u003cp\u003eMouse Gene ID: 83962\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: P58544\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46315721457843,"sku":"ES17946-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46315721490611,"sku":"ES17946-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies.jpg?v=1793190497","url":"https:\/\/afsbio.com\/products\/btbd1-rabbit-polyclonal-antibody-es17946","provider":"AFSBio Inc.","version":"1.0","type":"link"}