{"product_id":"bub1b-polyclonal-antibody-bt-ap06871","title":"BUB1B Polyclonal Antibody - BT-AP06871","description":"\u003cp\u003eBUB1B Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP06871-20, BT-AP06871-50, BT-AP06871-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex\/cyclosome (APC\/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Cell biology; Epigenetics and nuclear\u003c\/p\u003e \n\n\u003cp\u003eTarget Protein: BUB1B\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Mitotic checkpoint serine\/threonine-protein kinase BUB1 beta\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O60566; Mouse: Q9Z1S0\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Mitotic checkpoint serine\/threonine-protein kinase BUB1 beta;EC 2.7.11.1;MAD3\/BUB1-related protein kinase;hBUBR1;Mitotic checkpoint kinase MAD3L;Protein SSK1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 701\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239069638835,"sku":"BT-AP06871-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239069671603,"sku":"BT-AP06871-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239069704371,"sku":"BT-AP06871-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_eb16d9ee-a83e-4636-b2d0-71dd12a046fa.png?v=1769388700","url":"https:\/\/afsbio.com\/products\/bub1b-polyclonal-antibody-bt-ap06871","provider":"AFSBio Inc.","version":"1.0","type":"link"}