{"product_id":"bubr1-monoclonal-antibody-mb11941","title":"BUBR1 Monoclonal Antibody-MB11941","description":"\u003cp\u003eBUBR1 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB11941-50, MB11941-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: O60566\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Hamster\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-P, IP,\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000  IHC: 1\/50-1\/100  IP: 1\/20\u003c\/p\u003e  \n\n\u003cp\u003eBackground: Essential component of the mitotic checkpoint. Required for normal mitosis progression. The mitotic checkpoint delays anaphase until all chromosomes are properly attached to the mitotic spindle. One of its checkpoint functions is to inhibit the activity of the anaphase-promoting complex\/cyclosome (APC\/C) by blocking the binding of CDC20 to APC\/C, independently of its kinase activity. The other is to monitor kinetochore activities that depend on the kinetochore motor CENPE. Required for kinetochore localization of CENPE.\u003c\/p\u003e \n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 120 kDa; Observed MW: 120 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of BubR1 in CHO-K1, Ramos lysates using BUBR1 antibody., Immunohistochemistry analysis of paraffin-embedded Human lung cancer using BubR1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: BUB1B; BUBR1; MAD3L; SSK1; Mitotic checkpoint serine\/threonine-protein kinase BUB1 beta; MAD3\/BUB1-related protein kinase; hBUBR1; Mitotic checkpoint kinase MAD3L; Protein SSK1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of human BubR1\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42975395217587,"sku":"MB11941-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42975395250355,"sku":"MB11941-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_ad54b1fb-62e8-44b7-9f2c-49e74378284d.jpg?v=1705665372","url":"https:\/\/afsbio.com\/products\/bubr1-monoclonal-antibody-mb11941","provider":"AFSBio Inc.","version":"1.0","type":"link"}