{"product_id":"bubr1-polyclonal-antibody-bt-ap01012","title":"BubR1 Polyclonal Antibody - BT-AP01012","description":"\u003cp\u003eBubR1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP01012-20, BT-AP01012-50, BT-AP01012-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: BUB1B encodes a kinase involved in spindle checkpoint function. The protein (BUB1 mitotic checkpoint serine\/threonine kinase B)has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex\/cyclosome (APC\/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: BUB1B\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: BubR1 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 119545\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O60566; Mouse: Q9Z1S0\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: BUB1B; BUBR1; MAD3L; SSK1; Mitotic checkpoint serine\/threonine-protein kinase BUB1 beta; MAD3\/BUB1-related protein kinase; hBUBR1; Mitotic checkpoint kinase MAD3L; Protein SSK1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 701; Mouse: 12236\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240145871027,"sku":"BT-AP01012-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240145903795,"sku":"BT-AP01012-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240145936563,"sku":"BT-AP01012-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_6699197c-cd8a-445d-bfd5-b9782ccbc6aa.png?v=1769404152","url":"https:\/\/afsbio.com\/products\/bubr1-polyclonal-antibody-bt-ap01012","provider":"AFSBio Inc.","version":"1.0","type":"link"}