{"product_id":"c-ebp-α-phospho-s21-polyclonal-antibody-bs4217","title":"C\/EBP α (phospho-S21) Polyclonal Antibody-BS4217","description":"\u003cp\u003eC\/EBP α (phospho-S21) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS4217-50, BS4217-100\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P49715\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eC\/EBP α (phospho-S21) Polyclonal Antibody-BS4217\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003cbr\u003e\nIHC: 1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: C\/EBP α regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. C\/EBP α is a basic region\/leucine zipper transcription factor selectively expressed during the differentiation of liver, adipose tissue, blood cells and the endocrine pancreas. C\/EBP α uses a bipartite structural motif to bind DNA and appears to function exclusively in terminally differentiated, growtharrested cells. In the liver, C\/EBP α is a transactivator of several genes, which are regulated by growth hormone. Growth hormone enhances not only the levels of C\/EBP α mRNA and protein, but also the DNA-binding activity of C\/EBP α. C\/EBP α functions as an important transcription factor that regulates different genes, including Prolactin gene expression.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: p-C\/EBP α (S21) polyclonal antibody detects endogenous levels of C\/EBP α protein only when phosphorylated at Ser21.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 30,45 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of C\/EBP α (phospho-S21) polyclonal antibody at 1:500 dilution\u003cbr\u003e\n Lane 1: L02 whole cell lysate\u003cbr\u003e\n Lane 2: L02 treated with PBS (1×PBS,PH7.4) for 1 houre then treated with DMEM (10%FBS) for 5 minutes whole cell lysate\u003cbr\u003e\n Lane 3: L02 treated with PBS (1×PBS,PH7.4) for 1 houre then treated with DMEM (10%FBS) for 10 minutes whole cell lysate\u003cbr\u003e\n Lane 4: L02 treated with PBS (1×PBS,PH7.4) for 1 houre then treated with DMEM (10%FBS) for 15 minutes whole cell lysate, Immunohistochemistry (IHC) analyzes of p-C\/EBP α (S21) pAb in paraffin-embedded human lung carcinoma tissue at 1:100.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: CCAAT\/enhancer-binding protein alpha; C\/EBP alpha; CEBPA; C\/EBP α; C\/EBPα\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic phosphopeptide derived from human C\/EBP α around the phosphorylation site of Serine 21.\u003c\/p\u003e\n\n\u003cp\u003eModification: Phosphorylation\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42957296828595,"sku":"BS4217-50","price":276.71,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42957296861363,"sku":"BS4217-100","price":490.83,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_14f2d76e-94dd-406f-8095-d3cfc1c1f61d.jpg?v=1705144511","url":"https:\/\/afsbio.com\/products\/c-ebp-%ce%b1-phospho-s21-polyclonal-antibody-bs4217","provider":"AFSBio Inc.","version":"1.0","type":"link"}