{"product_id":"c-ebp-α-polyclonal-antibody-ra20915","title":"C\/EBP α Polyclonal Antibody - RA20915","description":"\u003cp\u003eC\/EBP α Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA20915-50, RA20915-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: CCAAT\/enhancer binding protein alpha (CEBPA) Homo sapiens This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT\/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons. [provided by RefSeq, Dec 2013],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/5000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: CEBPA; CCAAT\/enhancer-binding protein alpha; C\/EBP alpha\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC-p; IF (paraffin section) ; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse; Rat; Monkey\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 1050\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 37\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P49715\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45120701071539,"sku":"RA20915-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45120701104307,"sku":"RA20915-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_0019a6cd-055b-45fd-89e8-394360fbdf97.png?v=1773369764","url":"https:\/\/afsbio.com\/products\/c-ebp-%ce%b1-polyclonal-antibody-ra20915","provider":"AFSBio Inc.","version":"1.0","type":"link"}