{"product_id":"c-ebp-β-acetyl-lys265-rabbit-polyclonal-antibody-ra22530","title":"C\/EBP β (Acetyl Lys265) Rabbit Polyclonal Antibody - RA22530","description":"\u003cp\u003eC\/EBP β (Acetyl Lys265) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA22530-50, RA22530-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: function:Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses. Specifically binds to an IL-1 response element in the IL-6 gene. NF-IL6 also binds to regulatory regions of several acute-phase and cytokines genes. It probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'.,PTM:Sumoylated by polymeric chains of SUMO2 or SUMO3.,similarity:Belongs to the bZIP family.,similarity:Belongs to the bZIP family. C\/EBP subfamily.,similarity:Contains 1 bZIP domain.,subunit:Binds DNA as a dimer and can form stable heterodimers with C\/EBP alpha, delta and gamma. Interacts with TRIM28 and PTGES2.,tissue specificity:Expressed at low levels in the lung, kidney and spleen.,\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: WB 1:1000-2000 ELISA 1:5000-20000\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: CCAAT\/enhancer-binding protein beta (C\/EBP beta;Liver activator protein;Nuclear factor NF-IL6;Transcription factor 5;TCF-5)\u003c\/p\u003e \n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 1051\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 40\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P17676\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121116111027,"sku":"RA22530-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121116143795,"sku":"RA22530-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_ce67bf63-2e68-4ceb-8684-d2707d367fe6.png?v=1773371348","url":"https:\/\/afsbio.com\/products\/c-ebp-%ce%b2-acetyl-lys265-rabbit-polyclonal-antibody-ra22530","provider":"AFSBio Inc.","version":"1.0","type":"link"}