{"product_id":"c-ebp-β-phospho-thr235-rabbit-pab-es1275","title":"C\/EBP β (phospho Thr235) rabbit pAb - ES1275","description":"\u003cp\u003eC\/EBP β (phospho Thr235) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES1275-50, ES1275-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain. The encoded protein functions as a homodimer but can also form heterodimers with CCAAT\/enhancer-binding proteins alpha, delta, and gamma. Activity of this protein is important in the regulation of genes involved in immune and inflammatory responses, among other processes. The use of alternative in-frame AUG start codons results in multiple protein isoforms, each with distinct biological functions. [provided by RefSeq, Oct 2013],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: CEBPB; LAP; TCF5; PP9092; CCAAT\/enhancer-binding protein beta; C\/EBP beta; Liver activator protein; Nuclear factor NF-IL6; Transcription factor 5; TCF-5\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. Immunofluorescence: 1\/200 - 1\/1000. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human C\/EBP-beta around the phosphorylation site of Thr235\/188. AA range:201-250\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 36kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 1051\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P17676\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Nucleus. Cytoplasm. Translocates to the nucleus when phosphorylated at Ser-288. In T-cells when sumoylated drawn to pericentric heterochromatin thereby allowing proliferation (By similarity).\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202004836531,"sku":"ES1275-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202004869299,"sku":"ES1275-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_9e9471b0-c933-402d-aa1c-bad1b541b226.png?v=1767119765","url":"https:\/\/afsbio.com\/products\/c-ebp-%ce%b2-phospho-thr235-rabbit-pab-es1275","provider":"AFSBio Inc.","version":"1.0","type":"link"}