{"product_id":"c-ebp-β-polyclonal-antibody-bs90153","title":"C\/EBP β Polyclonal Antibody-BS90153","description":"\u003cp\u003eC\/EBP β Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS90153-50, BS90153-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P17676(Human) P28033(Mouse) P21272(Rat)\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ICC\/IF, IP, , FC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB:1:1,000-1:2,000\u003cbr\u003e\nICC:1:50-1:200\u003cbr\u003e\nFC:1:50-1:100\u003c\/p\u003e\n\n\u003cp\u003eBackground: CCAAT-enhancer binding proteins (C\/EBP) are basic region\/leucine zipper (bZIP) transcription factors selectively expressed during the differentiation of liver, adipose tissue, blood cells and the endocrine pancreas. C\/EBP β is a member of the C\/EBP transcription factor family. The C\/EBP β gene encodes several isoforms containing truncated transcription activation domains due to the alternative translational initiation at multipe AUG start sites. C\/EBP β is also known as interleukin 6-dependent DNA-binding protein (IL6DBP), liver activator protein (LAP) or liver-enriched transcriptional activator protein transcription factor 5 (TCF5). C\/EBP β contributes to the regulation of the acute phase response in hepatocytes. Stat3 has an important function in IL-6-mediated transcription of the C\/EBP β gene that has direct implication for acute phase response in liver cells.The C\/EBP β form requires phosphorylation for its DNA binding ability, and increase binding of C\/EBP β isoforms during acute-phase reaction occurs through its upregulation and structural modification.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: ProA affinity purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: C\/EBP β polyclonal antibody detects endogenous levels of C\/EBP β protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: 36 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of C\/EBP Beta on different lysates using anti-C\/EBP Beta antibody at 1\/1,000 dilution. \u003cbr\u003e\n Positive control: \u003cbr\u003e\n Lane 1: Hela \u003cbr\u003e\n Lane 2: PC-12, ICC staining C\/EBP Beta in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100\/PBS.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: C\/EBP beta, LAP, LIP, TCF-5, CEBPB, TCF5, AGP\/EBP, C EBP beta, C\/EBP beta, C\/EBP related protein 2, CCAAT Enhancer Binding Protein beta, CCAAT\/enhancer-binding protein beta, CEBPB, CEBPB, CRP2, IL 6DBP, IL6DBP, Interleukin 6 dependent binding protein, LAP, Liver activator protein, Liver enriched transcriptional activator, NF IL6, NFIL6, Nuclear factor NF IL6, Nuclear factor NF-IL6, SF B, SFB, Silencer factor B, TCF-5, TCF5, Transcription factor 5,\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: recombinant protein\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42979765289139,"sku":"BS90153-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42979765321907,"sku":"BS90153-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_794d61c4-6da5-4b4d-8ed1-e894fa13f6cd.jpg?v=1705748935","url":"https:\/\/afsbio.com\/products\/c-ebp-%ce%b2-polyclonal-antibody-bs90153","provider":"AFSBio Inc.","version":"1.0","type":"link"}