{"product_id":"c-ebp-γ-polyclonal-antibody-bs8806","title":"C\/EBP-γ Polyclonal Antibody-BS8806","description":"\u003cp\u003eC\/EBP-γ Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS8806-50, BS8806-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P53567\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, IF\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1:500~1:2000\u003cbr\u003e\nIHC: 1:50~1:200\u003cbr\u003e\nIF: 1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: The transcription factor C\/EBP α (CCAAT-enhancer binding protein) is a heatstable, sequence-specific DNA-binding protein first purified from rat liver nuclei that binds avidly to several different cis-regulatory DNA sequences commonly associated with viral and cellular genes transcribed by RNA polymerase II. C\/EBP α regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. C\/EBP α uses a bipartite structural motif to bind DNA. Two protein chains dimerize through a set of amphipathic alpha helices termed the leucine zipper. Highly basic polypeptide regions emerge from the zipper to form a linked set of DNA contact surfaces. C\/EBP α appears to function exclusively in terminally differentiated, growth-arrested cells. Additional family members include C\/EBP β, C\/EBP γ,C\/EBP δ and C\/EBP ε, all of which exhibit similar DNA-binding specificities and affinities to C\/EBP α. Furthermore, C\/EBP β and C\/EBP δ readily form heterodimers both with each other as well as with C\/EBP α.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: C\/EBP-γ polyclonal antibody detects endogenous levels of C\/EBP-γ protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 16kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western Blot analysis of extracts of various cell lines, using C\/EBP-γ antibody.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: CCAAT\/enhancer-binding protein gamma; C\/EBP gamma; CEBPG; C\/EBPγ; CEBPγ\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant full length Human C\/EBP-γ.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42923479924915,"sku":"BS8806-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42923479957683,"sku":"BS8806-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_bc0b55ac-68ef-42a5-a5b3-e7711321a48f.jpg?v=1703850267","url":"https:\/\/afsbio.com\/products\/c-ebp-%ce%b3-polyclonal-antibody-bs8806","provider":"AFSBio Inc.","version":"1.0","type":"link"}