{"product_id":"c-ebp-ε-k220-polyclonal-antibody-bs2074","title":"C\/EBP-ε (K220) Polyclonal Antibody-BS2074","description":"\u003cp\u003eC\/EBP-ε (K220) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS2074-50, BS2074-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q15744\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: IHC: 1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: C\/EBP α regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. C\/EBP α uses a bipartite structural motif to bind DNA. Two protein chains dimerize through a set of amphipathic α helices termed the leucine zipper. Highly basic polypeptide regions emerge from the zipper to form a linked set of DNA contact surfaces. C\/EBP α appears to function exclusively in terminally-differentiated, growth-arrested cells. Additional family members include C\/EBP β, C\/EBP γ, C\/EBP δ and C\/EBP ε, all of which exhibit similar DNA-binding specificities and affinities to C\/EBP α. Furthermore, C\/EBP β and C\/EBP δ readily form heterodimers both with each other as well as with C\/EBP α.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Immunohistochemistry (IHC) analyzes of C\/EBP-ε (K220) pAb in paraffin-embedded human liver carcinoma tissue at 1:50. showing nucleus staining. Negative control (the right) Using PBS instead of primary antibody,Secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 30, 45 kDa\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: C\/EBP-ε (K220) polyclonal antibody detects endogenous levels of C\/EBP-ε protein.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: CCAAT\/enhancer-binding protein epsilon; C\/EBP epsilon; CEBPE; C\/EBPε\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 188-245 of Human C\/EBP-ε.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42939290124467,"sku":"BS2074-50","price":254.38,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42939290190003,"sku":"BS2074-100","price":442.75,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_2fcc3c80-2068-441c-af08-099d44135a7a.jpg?v=1704545800","url":"https:\/\/afsbio.com\/products\/c-ebp-%ce%b5-k220-polyclonal-antibody-bs2074","provider":"AFSBio Inc.","version":"1.0","type":"link"}