{"product_id":"c-ebp-ζ-d24-polyclonal-antibody-bs2297","title":"C\/EBP ζ (D24) Polyclonal Antibody-BS2297","description":"\u003cp\u003eC\/EBP ζ (D24) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS2297-50, BS2297-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q03701\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eBackground: C\/EBP family members include C\/EBP α, C\/EBP β, C\/EBP γ, C\/EBP δ, C\/EBP ε and C\/EBP ζ, all of which are capable of forming homodimers or heterodimers with each other. C\/EBP ζ, also known as CBF2, NOC1, CHOP10 (C\/EBP homologous protein 10), GADD153 (growth arrest and DNA damage-inducible gene 153) or HSPCBF, is a ubiquitously expressed 1,054 amino acid protein that localizes to the nucleus and regulates transcription. More specifically, C\/EBP ζ is believed to play a role regulating the expression of CRP (C-reactive protein). Unlike most C\/EBP dimers, C\/EBP ζ-containing dimers do not bind the classical C\/EBP-binding consensus sequence. Rather, C\/EBP ζ-containing dimers must associate with RBP-Jκ (another transcription factor) in order to accomplish binding to the C\/EBP site.\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: C\/EBP ζ (D24) polyclonal antibody detects endogenous levels of C\/EBP ζ protein.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of C\/EBP ζ (D24) pAb at 1:500 dilution\u003cbr\u003e\nLane 1: PC12 whole cell lysate (40ug)\u003cbr\u003e\nLane 2: 3T3-L1 whole cell lysate (40ug)\u003cbr\u003e\nLane 3: A2780 whole cell lysate (40ug)\u003cbr\u003e\nLane 4: Hela whole cell lysate (40ug)\u003cbr\u003e\nLane 5: MCF-7 whole cell lysate (40ug), Immunohistochemistry (IHC) analyzes of C\/EBP ζ (D24) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.\u003c\/p\u003e \n\n\u003cp\u003eBioworld Molecular Weight: ~121 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: CBF2; CCAAT binding factor; CCAAT box binding transcription factor; CCAAT\/enhancer binding protein zeta; Cebpz; HSPCBF; CBF;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to the N-terminus of Human C\/EBP ζ.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42953223471283,"sku":"BS2297-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42953223504051,"sku":"BS2297-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_d7dc0a3c-9663-4a88-82bb-e21acac31c66.jpg?v=1705057096","url":"https:\/\/afsbio.com\/products\/c-ebp-%ce%b6-d24-polyclonal-antibody-bs2297","provider":"AFSBio Inc.","version":"1.0","type":"link"}