{"product_id":"c-fgr-monoclonal-antibody-ra10971","title":"c-Fgr Monoclonal Antibody - RA10971","description":"\u003cp\u003ec-Fgr Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSize: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA10971-50, RA10971-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: FGR proto-oncogene, Src family tyrosine kinase (FGR) Homo sapiens This gene is a member of the Src family of protein tyrosine kinases (PTKs) . The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC-p; IF (paraffin section) ; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 2268\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P09769\u003c\/p\u003e\n\n\u003cp\u003eSource: Mouse\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45118955290803,"sku":"RA10971-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45118955323571,"sku":"RA10971-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_3b5148f4-3026-4ef1-b81e-e0e8af4ce8dc.png?v=1773343675","url":"https:\/\/afsbio.com\/products\/c-fgr-monoclonal-antibody-ra10971","provider":"AFSBio Inc.","version":"1.0","type":"link"}