{"product_id":"c-rel-polyclonal-antibody-bt-ap02220","title":"c-Rel Polyclonal Antibody - BT-AP02220","description":"\u003cp\u003ec-Rel Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP02220-20, BT-AP02220-50, BT-AP02220-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: REL (REL proto-oncogene, NF-kB subunit) encodes a protein that belongs to the Rel homology domain\/immunoglobulin-like fold, plexin, transcription factor (RHD\/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of REL is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in REL are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: REL\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: c-Rel Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 68520\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q04864; Mouse: P15307\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: REL; Proto-oncogene c-Rel\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5966\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240233623731,"sku":"BT-AP02220-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240233656499,"sku":"BT-AP02220-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240233689267,"sku":"BT-AP02220-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_6f3c9282-8674-49eb-ae1c-e21669e1ae1f.png?v=1769405483","url":"https:\/\/afsbio.com\/products\/c-rel-polyclonal-antibody-bt-ap02220","provider":"AFSBio Inc.","version":"1.0","type":"link"}