{"product_id":"c11b2-polyclonal-antibody-bt-ap06943","title":"C11B2 Polyclonal Antibody - BT-AP06943","description":"\u003cp\u003eC11B2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP06943-20, BT-AP06943-50, BT-AP06943-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cardiovascular; Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CYP11B2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Cytochrome P450 11B2, mitochondrial\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P19099; Mouse: P15539; Rat: P30099\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Cytochrome P450 11B2, mitochondrial;Aldosterone synthase;ALDOS;EC 1.14.15.4;EC 1.14.15.5;Aldosterone-synthesizing enzyme;CYPXIB2;Cytochrome P-450Aldo;Cytochrome P-450C18;Steroid 18-hy\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 1585\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239069933747,"sku":"BT-AP06943-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239069966515,"sku":"BT-AP06943-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239069999283,"sku":"BT-AP06943-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_024b6b23-cbd1-498a-a7a1-1f013e7d97c4.png?v=1769388704","url":"https:\/\/afsbio.com\/products\/c11b2-polyclonal-antibody-bt-ap06943","provider":"AFSBio Inc.","version":"1.0","type":"link"}