{"product_id":"c12orf5-polyclonal-antibody-e-ab-16101","title":"C12orf5 Polyclonal Antibody - E-AB-16101","description":"\u003cp\u003eC12orf5 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-16101-60, E-AB-16101-120, E-AB-16101-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: C12orf5\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: 6-bisphosphatase TIGAR; C12ORF5; chromosome 12 open reading frame 5; FR2BP; Fructose-2; 6-bisphosphatase TIGAR; Fructose-2; 6-bisphosphate 2-phosphatase; Probable fructose 2; 6 bisphosphatase TIGAR; Probable fructose-2; tigar; TIGAR; TP53 induced glycolysis and apoptosis regulator; TP53 induced glycolysis regulatory phosphatase; TP53-induced glycolysis and apoptosis regulator; Transactivated by NS3TP2 protein\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9NQ88\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2, 6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.4 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human C12orf5\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:100-1:300\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43130613399731,"sku":"E-AB-16101-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43130613432499,"sku":"E-AB-16101-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43130613465267,"sku":"E-AB-16101-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_ae8424c9-a14e-47b6-8d1b-933efe83e8ee.png?v=1709810075","url":"https:\/\/afsbio.com\/products\/c12orf5-polyclonal-antibody-e-ab-16101","provider":"AFSBio Inc.","version":"1.0","type":"link"}