{"product_id":"c1rl-polyclonal-antibody-bt-ap14570","title":"C1RL Polyclonal Antibody - BT-AP14570","description":"\u003cp\u003eC1RL Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP14570-20, BT-AP14570-50, BT-AP14570-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Does not associate with the C1 complex. According to PubMed:15385675 doesn't cleave the proform of complement C1s.,Mediates the proteolytic cleavage of HP\/haptoglobin in the endoplasmic reticulum.,induction:Up-regulated in monocytes and dendritic cells (DC) undergoing maturation or activation.,Belongs to the peptidase S1 family.,Contains 1 CUB domain.,Contains 1 peptidase S1 domain.,tissue specificity:Highly expressed in placenta, liver, kidney, pancreas, moderately in lung, spleen, prostate, ovary, colon, and PBL, and weakly in heart, skeletal muscle, thymus, testis, and small intestine. Expressed in PC-3 (prostate adenocarcinoma) and SK-OV-3 (ovary adenocarcinoma) cells, but not in LoVo and HT-29 (colon adenocarcinoma), SMMC7721 (hepatocellular carcinoma), CaoV-3 (ovary adenocarcinoma), HeLa (cervix epithelioid carcinoma), MCF-7 (breast adenocarcinoma), U251 (glioma) or A549 (lung carcinoma) cells. Widely expressed in myeloid leukemia cell lines, including K-562 (chronic myelogenous leukemia), THP-1 (myelomonocytic leukemia), HL-60 and NB4 (promyelocytic leukemia), and KG-1 (acute myelogenous leukemia) cells. Expressed mainly in the liver and in serum (at protein level).,\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell biology\u003c\/p\u003e \n\n\u003cp\u003eTarget Protein: C1RL\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: C1RL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9NZP8; Mouse: Q3UZ09\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: C1RL; Complement C1r subcomponent-like protein; C1r-LP; C1r-like protein; EC 3.4.21.-; C1r-like serine protease analog protein; CLSPa\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 51279; Mouse: 232371\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239070392499,"sku":"BT-AP14570-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239070425267,"sku":"BT-AP14570-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239070458035,"sku":"BT-AP14570-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_f9beb12d-c087-4497-b0f0-2fb2b2ac40e3.png?v=1769388710","url":"https:\/\/afsbio.com\/products\/c1rl-polyclonal-antibody-bt-ap14570","provider":"AFSBio Inc.","version":"1.0","type":"link"}