{"product_id":"c3-polyclonal-antibody-e-ab-93167","title":"C3 Polyclonal Antibody - E-AB-93167","description":"\u003cp\u003eC3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-93167-60, E-AB-93167-120, E-AB-93167-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: C3\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: C3; AHUS5; ARMD9; ASP; C3a; C3b; CPAMD1; HEL-S-62p; complement C3; C3 \/ C3a\u003c\/p\u003e\n\n \n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P01027\u003c\/p\u003e\n\n\u003cp\u003eBackground: Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of mouse C3\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 187kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 115kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43145987817651,"sku":"E-AB-93167-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43145987850419,"sku":"E-AB-93167-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43145987883187,"sku":"E-AB-93167-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_f2dab2c2-e3fc-4d2f-9557-24ecdae5d55c.png?v=1710289328","url":"https:\/\/afsbio.com\/products\/c3-polyclonal-antibody-e-ab-93167","provider":"AFSBio Inc.","version":"1.0","type":"link"}