{"product_id":"cables1-polyclonal-antibody-bt-ap01073","title":"Cables1 Polyclonal Antibody - BT-AP01073","description":"\u003cp\u003eCables1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP01073-20, BT-AP01073-50, BT-AP01073-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: CABLES1 encodes a protein (Cdk5 and Abl enzyme substrate 1) involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127). Multiple transcript variants encoding different isoforms have been found for CABLES1.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CABLES1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Cables1 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 67599\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q8TDN4; Mouse: Q9ESJ1\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: CABLES1; CABLES; CDK5 and ABL1 enzyme substrate 1; Interactor with CDK3 1; Ik3-1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 91768; Mouse: 63955\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240150130867,"sku":"BT-AP01073-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240150163635,"sku":"BT-AP01073-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240150196403,"sku":"BT-AP01073-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_fcb38924-c60a-4488-8fdb-30a9dcf3a53d.png?v=1769404218","url":"https:\/\/afsbio.com\/products\/cables1-polyclonal-antibody-bt-ap01073","provider":"AFSBio Inc.","version":"1.0","type":"link"}