{"product_id":"cac1a-polyclonal-antibody-bt-ap06997","title":"CAC1A Polyclonal Antibody - BT-AP06997","description":"\u003cp\u003eCAC1A Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP06997-20, BT-AP06997-50, BT-AP06997-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2\/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas, the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1A subunit, which is predominantly expressed in neuronal tissue. Mutations in this gene are associated with 2 neurologic disorders, familial hemiplegic migraine and episodic ataxia 2. This gene also exhibits\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer; Metabolism; Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CACNA1A\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, IF\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Voltage-dependent P\/Q-type calcium channel subunit alpha-1A\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O00555; Mouse: P97445; Rat: P54282\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Voltage-dependent P\/Q-type calcium channel subunit alpha-1A;Brain calcium channel I;BI;Calcium channel, L type, alpha-1 polypeptide isoform 4;Voltage-gated calcium channel subunit alpha Cav2.1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 773\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239071637683,"sku":"BT-AP06997-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239071670451,"sku":"BT-AP06997-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239071703219,"sku":"BT-AP06997-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_c106eac5-fabe-4d64-9c86-e867613b9e49.png?v=1769388725","url":"https:\/\/afsbio.com\/products\/cac1a-polyclonal-antibody-bt-ap06997","provider":"AFSBio Inc.","version":"1.0","type":"link"}