{"product_id":"cac1e-polyclonal-antibody-bt-ap14592","title":"CAC1E Polyclonal Antibody - BT-AP14592","description":"\u003cp\u003eCAC1E Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP14592-20, BT-AP14592-50, BT-AP14592-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Voltage-dependent calcium channels are multisubunit complexes consisting of alpha-1, alpha-2, beta, and delta subunits in a 1:1:1:1 ratio. These channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This gene encodes the alpha-1E subunit of the R-type calcium channels, which belong to the andapos;high-voltage activatedandapos; group that maybe involved in the modulation of firing patterns of neurons important for information processing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Metabolism; Neuroscience; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CACNA1E\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, IF\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Voltage-dependent R-type calcium channel subunit alpha-1E\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q15878; Mouse: Q61290; Rat: Q07652\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Voltage-dependent R-type calcium channel subunit alpha-1E;Brain calcium channel II;BII;Calcium channel, L type, alpha-1 polypeptide, isoform 6;Voltage-gated calcium channel subunit alpha Cav2.3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 777\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239071735987,"sku":"BT-AP14592-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239071768755,"sku":"BT-AP14592-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239071801523,"sku":"BT-AP14592-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_5d4814b4-e2a2-4a13-ae2e-f4f1a82e1cfe.png?v=1769388726","url":"https:\/\/afsbio.com\/products\/cac1e-polyclonal-antibody-bt-ap14592","provider":"AFSBio Inc.","version":"1.0","type":"link"}