{"product_id":"cacna1h-rabbit-pab-a25219","title":"CACNA1H Rabbit pAb - A25219","description":"\u003cp\u003eCACNA1H Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A25219-20, A25219-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a T-type member of the alpha-1 subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2\/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants, encoding different isoforms, have been characterized for the gene described here. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (CAE) .\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: IF-P, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Rat\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 259kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: Refer to figures\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide .\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 8912\u003c\/p\u003e\n\n\u003cp\u003eSWISS: O95180\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: ECA6; EIG6; HALD4; Cav3.2; CACNA1HB; CACNA1H\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: IF-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction, Neuroscience, Calcium Signaling.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: CACNA1H\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189867012275,"sku":"A25219-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189867045043,"sku":"A25219-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_58552339-68f4-4388-9da6-c61dcfc90336.png?v=1766437068","url":"https:\/\/afsbio.com\/products\/cacna1h-rabbit-pab-a25219","provider":"AFSBio Inc.","version":"1.0","type":"link"}