{"product_id":"caldesmonab-759polyclonal-antibody-bs65240","title":"Caldesmon(Ab-759)Polyclonal Antibody-BS65240","description":"\u003cp\u003eCaldesmon(Ab-759)Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS65240-50, BS65240-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q05682\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\/IgG2b, Kappa\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, IF (paraffin section)\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: IHC-p 1:100-500，WB 1:500-2000\u003c\/p\u003e\n\n\u003cp\u003eBackground: caldesmon 1(CALD1) Homo sapiens This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: This antibody detects endogenous levels of human Caldesmon. Heat-induced epitope retrieval (HIER) TRIS-EDTA of pH8.0 was highly recommended as antigen repair method in paraffin section\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human Caldesmon\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Immunohistochemical analysis of paraffin-embedded Liomyoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min)., Immunohistochemical analysis of paraffin-embedded Colon. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min)., Western blot analysis of CaldesmonAntibody at 1:1000 dilution.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42892340265139,"sku":"BS65240-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42892340297907,"sku":"BS65240-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_d0797cd4-edc3-496d-9738-3e6c4d8829e5.jpg?v=1702483312","url":"https:\/\/afsbio.com\/products\/caldesmonab-759polyclonal-antibody-bs65240","provider":"AFSBio Inc.","version":"1.0","type":"link"}