{"product_id":"calmodμlin-phospho-t80-s82-polyclonal-antibody-bs66189","title":"Calmodμlin (Phospho-T80\/S82) Polyclonal Antibody - BS66189","description":"\u003cp\u003eCalmodμlin (Phospho-T80\/S82) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS66189-50, BS66189-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: Calmodμlin is a ubiquitously expressed small protein mediating many cellμlar effects such as short-term and long-term memory, nerve growth, inflammation, apoptosis, muscle contraction and intracellμlar movement. Upon binding of four Ca2+ ions, calmodμlin undergoes conformational changes, allowing this complex to bind to and activate many enzymes including protein kinases, protein phosphatases, ion channels, Ca2+ pumps, nitric oxide synthase, inositol triphosphate kinase, and cyclic nucleotide phosphodiesterase. Since calmodμlin binds Ca2+ in a cooperative fashion, small changes in cytosolic Ca2+ levels lead to large changes in the level of active calmodμlin and its target proteins.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF\/ICC, IHC\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: CALM, CAM, CAM1, CAM2, CAMB, CALML2, CAM3, CAMC, CAMIII, Calmodμlin, CaM\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Phosphorylation\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: KLH-conjugated synthetic phosphopeptide corresponding to residues surrounding T80\/S82 of human Calmodμlin protein.\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB: 1:500-1:1000\u003cbr\u003e\nIF\/ICC: 1:100-1:500\u003cbr\u003e\nIHC: 1:100-1:200\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Recognizes endogenous levels of Calmodμlin protein only when phosphorylated at T80\/S82.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: ~ 17 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: P62158\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45938580586675,"sku":"BS66189-50","price":289.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45938580619443,"sku":"BS66189-100","price":492.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image_7d54f7f7-895a-4faa-805b-93c7ca9b170c.jpg?v=1788296274","url":"https:\/\/afsbio.com\/products\/calmod%ce%bclin-phospho-t80-s82-polyclonal-antibody-bs66189","provider":"AFSBio Inc.","version":"1.0","type":"link"}