{"product_id":"calpain-2-k354-polyclonal-antibody-bs3696","title":"Calpain 2 (K354) Polyclonal Antibody-BS3696","description":"\u003cp\u003eCalpain 2 (K354) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS3696-50, BS3696-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P17655\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e \n\n\u003cp\u003eBackground: Mu Calpain, and m calpain, also known as Calpain 2, are intracellular, calcium dependent cysteine proteases. Mu calpain has a micromolar sensitivity (thus the mu) as compared to the millimolar calcium sensitivity of m calpain. Both Calpains 1 and 2 are composed of an 80 kD subunit and a 30 kD subunit. Whereas the 30 kDa subunit is shared by both enzymes, the larger catalytic subunits are different and exhibit the distinct Ca++ requirements that are suggested by their names.\u003c\/p\u003e \n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Calpain 2 (K354) polyclonal antibody detects endogenous levels of Calpain-2 catalytic subunit protein.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of Calpain 2 (K354) pAb at 1:500 dilution\u003cbr\u003e\nLane 1: Beas-2B whole cell lysate (40ug)\u003cbr\u003e\nLane 2: HEK293T whole cell lysate (40ug)\u003cbr\u003e\nLane 3: PC3 whole cell lysate (40ug)\u003cbr\u003e\nLane 4: The Kidney tissue lysate of Mouse (40ug)\u003cbr\u003e\nLane 5: The Kidney tissue lysate of Rat (40ug), Immunohistochemistry (IHC) analyzes of Calpain 2 (K354) pAb in paraffin-embedded human brain tissue.\u003c\/p\u003e \n\n\u003cp\u003eBioworld Molecular Weight: ~ 80 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Calpain-2 catalytic subunit; Calcium-activated neutral proteinase 2; CANP 2; Calpain M-type; Calpain large polypeptide L2; Calpain-2 large subunit; Millimolar-calpain; M-calpain; CANPL2; CAPN2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 320-370 of Human Calpain 2.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42953205022899,"sku":"BS3696-50","price":254.38,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42953205055667,"sku":"BS3696-100","price":442.75,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_7e44cc49-263e-45bf-adbb-16eb6bb9af8a.jpg?v=1705056722","url":"https:\/\/afsbio.com\/products\/calpain-2-k354-polyclonal-antibody-bs3696","provider":"AFSBio Inc.","version":"1.0","type":"link"}