{"product_id":"calumenin-polyclonal-antibody-bs6483","title":"Calumenin Polyclonal Antibody-BS6483","description":"\u003cp\u003eCalumenin Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS6483-50, BS6483-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: O43852\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, IF\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB\t1:500 - 1:2000  IHC\t1:50 - 1:200  IF\t1:50 - 1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: Caluminin is a 315 amino acid Ca2+-binding member of the CREC, EF-hand protein family. Calumenin is a secreted protein t hat contains six Ca2+-binding (EF-hand) motifs and is expressed in the lumen of the endoplasmic reticulum (ER) and Golgi apparatus. In the presence of Ca2+, Calumenin interacts with serum amyloid P component (SAP) and, together, they may play a role in the immunological defense system and participate in amyloidosis, the pathological formation of amyloid deposits in different types of tissues. Calumenin has an inhibitory effect on the vitamin K-dependent g-carboxylation system which converts vitamin K-dependent proteins to Gla-containing proteins. Calumenin may also be involved in the pathophysiology of thrombosis and\/or wound healing by acting in an autocrine or paracrine manner.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: CALU polyclonal antibody detects endogenous levels of CALU protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 50 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of extracts of various cells, using CALU antibody., Immunohistochemistry of paraffin-embedded mouse skin using CALU antibody at dilution of 1:100 (x40 lens)., Immunohistochemistry of paraffin-embedded rat lung using CALU antibody at dilution of 1:100 (x40 lens).\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Calumenin; Crocalbin; IEF SSP 9302; CALU\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant full length Human CALU.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42997576925363,"sku":"BS6483-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42997576958131,"sku":"BS6483-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_1fc05aa6-7aa8-4cdf-b5f8-9831634e9ff9.jpg?v=1706270618","url":"https:\/\/afsbio.com\/products\/calumenin-polyclonal-antibody-bs6483","provider":"AFSBio Inc.","version":"1.0","type":"link"}