{"product_id":"camkiiα-β-δ-phospho-thr305-rabbit-pab-es1415","title":"CaMKIIα\/β\/δ (phospho Thr305) rabbit pAb - ES1415","description":"\u003cp\u003eCaMKIIα\/β\/δ (phospho Thr305) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES1415-50, ES1415-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The product of this gene belongs to the serine\/threonine protein kinases family, and to the Ca (2+)\/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: CAMK2A; CAMKA; KIAA0968; Calcium\/calmodulin-dependent protein kinase type II subunit alpha; CaM kinase II subunit alpha; CaMK-II subunit alpha; CAMK2B; CAM2; CAMK2; CAMKB; Calcium\/calmodulin-dependent protein kinase type II subunit beta; Ca\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/5000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human CaMK2 alpha\/beta\/delta around the phosphorylation site of Thr305. AA range:271-320\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 54kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 816\/817\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q9UQM7\/Q13554\/Q13557\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cell junction, synapse. Cell junction, synapse, postsynaptic density. Cell projection, dendritic spine. Cell projection, dendrite. Postsynaptic lipid rafts.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202012733619,"sku":"ES1415-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202012766387,"sku":"ES1415-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_ade27aba-cc79-4e98-9f35-fee14d799d08.png?v=1767119925","url":"https:\/\/afsbio.com\/products\/camkii%ce%b1-%ce%b2-%ce%b4-phospho-thr305-rabbit-pab-es1415","provider":"AFSBio Inc.","version":"1.0","type":"link"}