{"product_id":"camkiiα-δ-phospho-thr286-polyclonal-antibody-ra22676","title":"CaMKIIα\/δ (phospho Thr286) Polyclonal Antibody - RA22676","description":"\u003cp\u003eCaMKIIα\/δ (phospho Thr286) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA22676-50, RA22676-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: calcium\/calmodulin dependent protein kinase II alpha (CAMK2A) Homo sapiens The product of this gene belongs to the serine\/threonine protein kinases family, and to the Ca (2+) \/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM) -dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. Immunofluorescence: 1\/200 - 1\/1000. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: CAMK2A; CAMKA; KIAA0968; Calcium\/calmodulin-dependent protein kinase type II subunit alpha; CaM kinase II subunit alpha; CaMK-II subunit alpha; CAMK2D; CAMKD; Calcium\/calmodulin-dependent protein kinase type II subunit delta; CaM kinase II\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC-p; IF\/ICC; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 815\/817\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 54\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q9UQM7\/Q13557\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121137606835,"sku":"RA22676-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121137639603,"sku":"RA22676-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_8a1b39a8-1a50-4687-a665-b13db380a94d.png?v=1773371474","url":"https:\/\/afsbio.com\/products\/camkii%ce%b1-%ce%b4-phospho-thr286-polyclonal-antibody-ra22676","provider":"AFSBio Inc.","version":"1.0","type":"link"}