{"product_id":"camkk2-polyclonal-antibody-bt-ap01150","title":"CaMKK2 Polyclonal Antibody - BT-AP01150","description":"\u003cp\u003eCaMKK2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP01150-20, BT-AP01150-50, BT-AP01150-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The product of CAMKK2 belongs to the Serine\/Threonine protein kinase family, and to the Ca(2+)\/calmodulin-dependent protein kinase subfamily. The major isoform of CAMKK2 plays a role in the calcium\/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CAMKK2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: CaMKK2 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 64732\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q96RR4; Mouse: Q8C078; Rat: O88831\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: CAMKK2; CAMKKB; KIAA0787; Calcium\/calmodulin-dependent protein kinase kinase 2; CaM-KK 2; CaM-kinase kinase 2; CaMKK 2; Calcium\/calmodulin-dependent protein kinase kinase beta; CaM-KK beta; CaM-kinase\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 10645; Mouse: 207565; Rat: 83506\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240155111603,"sku":"BT-AP01150-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240155144371,"sku":"BT-AP01150-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240155177139,"sku":"BT-AP01150-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_6bd6c404-9773-4bde-adcc-1618c9291872.png?v=1769404293","url":"https:\/\/afsbio.com\/products\/camkk2-polyclonal-antibody-bt-ap01150","provider":"AFSBio Inc.","version":"1.0","type":"link"}