{"product_id":"camkv-n217-polyclonal-antibody-bs2493","title":"CaMKV (N217) Polyclonal Antibody-BS2493","description":"\u003cp\u003eCaMKV (N217) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS2493-50, BS2493-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q8NCB2\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1:1000~1:2000\u003c\/p\u003e\n\n\u003cp\u003eBackground: The Ca2+\/calmodulin-dependent protein kinases (CaMKs) comprise a structurally related subfamily of serine\/threonine kinases. CAMKV (CaM kinaselike vesicle-associated), also known as 1G5 or VACAMKL, is a 501 amino acid protein that localizes to cytoplasmic vesicles, as well as to the cell membrane, and contains one protein kinase domain. Although a member of the CaMK family, CaMKV is thought to be catalytically inactive, but it may play a role in vesicle function and nervous system development. Multiple isoforms of CaMKV exist due to alternative splicing events. The gene encoding CaMKV maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and CharcotMarie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: CaMKV (N217) polyclonal antibody detects endogenous levels of CaMKV protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of CaMKV (N217) polyclonal antibody at 1:1000 dilution\u003cbr\u003e\nLane1:HEK293T whole cell lysate(40ug)\u003cbr\u003e\nLane2:U-87MG whole cell lysate(40ug)\u003cbr\u003e\nLane3:PC12 whole cell lysate(40ug)\u003cbr\u003e\nLane4:BV2 whole cell lysate(40ug)\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 54 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: CaM kinase-like vesicle-associated protein; CAMKV\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 186-247 of Human CaMKV.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42910482268339,"sku":"BS2493-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42910482301107,"sku":"BS2493-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_02e070c9-0282-4e41-887b-49352c6187de.jpg?v=1703093358","url":"https:\/\/afsbio.com\/products\/camkv-n217-polyclonal-antibody-bs2493","provider":"AFSBio Inc.","version":"1.0","type":"link"}