{"product_id":"caper-r199-polyclonal-antibody-bs1891","title":"Caper (R199) Polyclonal Antibody-BS1891","description":"\u003cp\u003eCaper (R199) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS1891-50, BS1891-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: O75787\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003c\/p\u003e\n\n\u003cp\u003eBackground: Caper, also known as splicing factor HCC1 or hepatocellular carcinoma protein 1 and RNA binding region containing protein 2 (RNPC2), acts as a transcriptional coactivator for steroid nuclear receptors c-Jun, ERα and ERβ. Caper, a nuclear protein with highest concentrations in nuclear speckles, plays a role in the pre-mRNA splicing process. Two isoforms of Caper, HCC1.3 and HCC1.4, co-localize with pre-mRNA splicing factor SC35 and uridine-rich small nuclear RNAs. Caper is a widely expressed protein with highest levels detected in skeletal muscle, lung, brain and pancreas.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Caper (R199) pAb detects endogenous levels of Caper (R199) protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of Caper (R199) pAb at 1:500 dilution\u003cbr\u003e\nLane1:C6 whole cell lysate(40ug)\u003cbr\u003e\nLane2:3T3-L1 whole cell lysate(40ug)\u003cbr\u003e\nLane3:HepG2 whole cell lysate(40ug)\u003cbr\u003e\nLane4:U-87MG whole cell lysate(40ug)\u003cbr\u003e\nLane5:HEK293T whole cell lysate(40ug)\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 39 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Histone H3.1; Histone H3\/a; Histone H3\/b; Histone H3\/c; Histone H3\/d; Histone H3\/f; Histone H3\/h; Histone H3\/i; Histone H3\/j; Histone H3\/k; Histone H3\/l; HIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; HIST1H3F; H3FI; HIST1H3G; H3FH; HIST1H3H; H3FK; HIST1H3I; H3FF; HIST1H3J; H3FJ; Histone H3.2; Histone H3\/m; Histone H3\/o; HIST2H3A; HIST2H3C; H3F2; H3FM; HIST2H3D; Histone H3.3; 3F3A; H3.3A; H3F3; PP781; H3F3B; H3.3B; Histone H3.3C; Histone H3.5; H3F3C\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic methylpeptide derived from human Histone H3 around the methylation site of Lysine 80.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42910476927155,"sku":"BS1891-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42910476959923,"sku":"BS1891-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_90b1a4cc-2cb6-49c9-8826-ded66b495da0.jpg?v=1703093192","url":"https:\/\/afsbio.com\/products\/caper-r199-polyclonal-antibody-bs1891","provider":"AFSBio Inc.","version":"1.0","type":"link"}