{"product_id":"card11-phospho-ser652-rabbit-polyclonal-antibody-bt-ap01038","title":"CARD11 (Phospho-Ser652) Rabbit Polyclonal Antibody - BT-AP01038","description":"\u003cp\u003eCARD11 (Phospho-Ser652) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP01038-20, BT-AP01038-50, BT-AP01038-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family| a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family| which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10| a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells| this protein activated NF-kappaB and induced the phosphorylation of BCL10.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Cell biology; Epigenetics and nuclear signaling; Immunology; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CARD11\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: CARD11\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9BXL7; Mouse: Q8CIS0\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: CARD11;Ser652; Caspase recruitment domain-containing protein 11; CARD-containing MAGUK protein 1; Carma 1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 84433; Mouse: 108723\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45238974546099,"sku":"BT-AP01038-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45238974578867,"sku":"BT-AP01038-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238974611635,"sku":"BT-AP01038-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_981c7357-92fa-4c4d-a69a-2e8116867793.png?v=1769387427","url":"https:\/\/afsbio.com\/products\/card11-phospho-ser652-rabbit-polyclonal-antibody-bt-ap01038","provider":"AFSBio Inc.","version":"1.0","type":"link"}