{"product_id":"card11-phospho-ser652-rabbit-polyclonal-antibody-ra22698","title":"CARD11 (phospho-Ser652) Rabbit Polyclonal Antibody - RA22698","description":"\u003cp\u003eCARD11 (phospho-Ser652) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA22698-50, RA22698-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: caspase recruitment domain family member 11 (CARD11) Homo sapiens The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD) . This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: WB 1:1000-2000\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 1) (Carma 1)\u003c\/p\u003e \n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 84433\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 130\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q9BXL7\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121140785331,"sku":"RA22698-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121140818099,"sku":"RA22698-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_e419d1ba-fd46-402b-b6fe-2f85cbcc1d0a.png?v=1773371503","url":"https:\/\/afsbio.com\/products\/card11-phospho-ser652-rabbit-polyclonal-antibody-ra22698","provider":"AFSBio Inc.","version":"1.0","type":"link"}