{"product_id":"cardiotrophin-1-h31-polyclonal-antibody-bs3672","title":"Cardiotrophin-1 (H31) Polyclonal Antibody-BS3672","description":"\u003cp\u003eCardiotrophin-1 (H31) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS3672-50, BS3672-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q16619\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e \n\n\u003cp\u003eBackground: Cardiotrophin-1 (CT-1) is a member of the IL-6 family of cytokines, which signal through gp130 receptor complexes. gp130 complexes with several different receptor subunits to transmit signals from Cardiotrophin-1, IL-6, LIF, OSM, CNTF and IL-11. Cardiotrophin-1 binds to and activates the leukemia inhibitory factor (LIF) receptor\/gp130 receptor complex and has been shown to induce hypertrophy in cardiac myocytes in vitro. Cardiotrophin-1, a secreted protein expressed at high levels in myocardium during cardiogenesis, has been shown to promote proliferation and survival of embryonic cardiomyocytes, suggesting a role for Cardiotrophin-1 in the activation of gp130 during cardiac development.\u003c\/p\u003e \n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Cardiotrophin-1 (H31) polyclonal antibody detects endogenous levels of Cardiotrophin-1 protein.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of Cardiotrophin-1 (H31) pAb at 1:500 dilution\u003cbr\u003e\nLane 1: PC3 whole cell lysate (40ug)\u003cbr\u003e\nLane 2: K562 whole cell lysate (20ug)\u003cbr\u003e\nLane 3: Jurkat whole cell lysate (40ug)\u003cbr\u003e\nLane 4: The Muscle tissue lysate of Mouse (40ug)\u003cbr\u003e\nLane 5: H9C2 whole cell lysate (40ug), Immunohistochemistry (IHC) analyzes of Cardiotrophin-1 (H31) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.\u003c\/p\u003e \n\n\u003cp\u003eBioworld Molecular Weight: ~ 21 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Cardiotrophin-1; CT-1; CTF1; Cardiotrophin1; CT1; Cardiotrophin 1; CT 1;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 1-53 of Human CT-1.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42953238872243,"sku":"BS3672-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42953238905011,"sku":"BS3672-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_24c02b81-1c40-4fbd-9187-38ad5a231266.jpg?v=1705057432","url":"https:\/\/afsbio.com\/products\/cardiotrophin-1-h31-polyclonal-antibody-bs3672","provider":"AFSBio Inc.","version":"1.0","type":"link"}