{"product_id":"cart-rabbit-polyclonal-antibody-es11102","title":"CART Rabbit Polyclonal Antibody - ES11102","description":"\u003cp\u003eCART Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES11102-50, ES11102-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a preproprotein that is proteolytically processed to generate multiple biologically active peptides. These peptides play a role in appetite, energy balance, maintenance of body weight, reward and addiction, and the stress response. Expression of a similar gene transcript in rodents is upregulated following administration of cocaine and amphetamine. Mutations in this gene are associated with susceptibility to obesity in humans. [provided by RefSeq, Feb 2016],\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from part region of human protein AA range: 1-50\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: CART\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: CART Polyclonal Antibody detects endogenous levels of protein.\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000 ELISA 1:5000-20000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Hypothalamus, Found in neurons of the ventrolateral part of the arcuate nucleus, in the external zone of the median eminence, and also found in terminals in the periventricular part of the paraventricular nucleus,\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 12kD\u003c\/p\u003e\n\n\u003cp\u003eFunction: Disease: A defect in CART is associated with reduced resting energy expenditure and cosegregates with obesity phenotype\u003cbr\u003e\nFunction: Satiety factor closely associated with the actions of leptin and neuropeptide y, this anorectic peptide inhibits both normal and starvation-induced feeding and completely blocks the feeding response induced by neuropeptide Y and regulated by leptin in the hypothalamus. It promotes neuronal development and survival in vitro\u003cbr\u003e\nInduction: By leptin\u003cbr\u003e\nSimilarity: Belongs to the CART family\u003cbr\u003e\nTissue Specificity: Hypothalamus. Found in neurons of the ventrolateral part of the arcuate nucleus, in the external zone of the median eminence, and also found in terminals in the periventricular part of the paraventricular nucleus\u003c\/p\u003e\n\n\n\u003cp\u003eSubcellular Location: Secreted\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: CARTPT CART\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: Cocaine- and amphetamine-regulated transcript protein [Cleaved into: CART(1-39), CART(42-89)]\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: P56388\u003c\/p\u003e\n\n\u003cp\u003eRat SwissProt Number: P49192\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46314377380019,"sku":"ES11102-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46314377412787,"sku":"ES11102-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies.jpg?v=1793190497","url":"https:\/\/afsbio.com\/products\/cart-rabbit-polyclonal-antibody-es11102","provider":"AFSBio Inc.","version":"1.0","type":"link"}