{"product_id":"casein-kinase-iδ-polyclonal-antibody-bs5640","title":"Casein Kinase Iδ Polyclonal Antibody-BS5640","description":"\u003cp\u003eCasein Kinase Iδ Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS5640-50, BS5640-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Casein kinase I isoform delta; CKI-delta; CKId; Tau-protein kinase CSNK1D; CSNK1D; HCKID; CKIδ; CK-Iδ; CK Iδ;\u003c\/p\u003e \n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P48730\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003c\/p\u003e\n\n\u003cp\u003eBackground: Casein kinase I (also designated CKI) and casein kinase II (also designated CKII) compose a family of serine\/threonine protein kinases which are present in all eukaryotes examined to date. CKI family members, which include CKIα, γ, ε and δ, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an α2β2 or an αα'β2 structure. The α catalytic subunit is stimulated by the β regulatory subunit, which undergoes autophosphorylation. CKII activity is high in the cytosol and nucleus of proliferating and differentiating cells. CKII is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Casein Kinase Iδ polyclonal antibody detects endogenous levels of Casein Kinase Iδ protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 47 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of Casein Kinase Iδ polyclonal antibody at 1:500 dilution\u003cbr\u003e\nLane 1: HepG2 cell lysate\u003cbr\u003e\nLane 2: Raw264.7 cell lysate\u003cbr\u003e\nLane 3: PC12 cell lysate\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 334-379 of Human Casein Kinase Iδ.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42911809896627,"sku":"BS5640-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42911809929395,"sku":"BS5640-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_69f8549d-cf89-4cf6-b3cd-73aa45f6d028.jpg?v=1703179719","url":"https:\/\/afsbio.com\/products\/casein-kinase-i%ce%b4-polyclonal-antibody-bs5640","provider":"AFSBio Inc.","version":"1.0","type":"link"}