{"product_id":"casein-kinase-i-α1-1l-rabbit-polyclonal-antibody-es4699","title":"Casein Kinase I α1\/1L Rabbit Polyclonal Antibody - ES4699","description":"\u003cp\u003eCasein Kinase I α1\/1L Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES4699-50, ES4699-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling.,similarity:Belongs to the protein kinase superfamily. CK1 Ser\/Thr protein kinase family. Casein kinase I subfamily.,similarity:Contains 1 protein kinase domain.,\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC, IF, WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: CSNK1A1L, Casein kinase I isoform alpha-like, CKI-alpha-like, CK1, CSNK1A1, Casein kinase I isoform alpha, CKI-alpha, CK1\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human CKI-alpha1\/L. AA range:141-190\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: Casein Kinase I α1\/1L\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Casein Kinase I α1\/1L Polyclonal Antibody detects endogenous levels of Casein Kinase I α1\/1L protein.\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000 Immunohistochemistry: 1\/100 - 1\/300. Immunofluorescence: 1\/200 - 1\/1000. ELISA: 1\/20000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Testis,\u003c\/p\u003e \n\n\u003cp\u003eObserved Band (KD): 30kD\u003c\/p\u003e\n\n\u003cp\u003eFields: Wnt signaling pathway, Hedgehog signaling pathway, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Human papillomavirus infection, Breast cancer, Hepatocellular carcinoma, Gastric cancer\u003c\/p\u003e\n\n\u003cp\u003eFunction: Catalytic Activity: ATP + a protein = ADP + a phosphoprotein\u003cbr\u003e\nFunction: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling\u003cbr\u003e\nSimilarity: Belongs to the protein kinase superfamily. CK1 Ser\/Thr protein kinase family. Casein kinase I subfamily\u003cbr\u003e\nSimilarity: Contains 1 protein kinase domain\u003c\/p\u003e\n\n\n\u003cp\u003eSubcellular Location: Cytoplasm\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: CSNK1A1\/CSNK1A1L\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: Casein kinase I isoform alpha\/Casein kinase I isoform alpha-like\u003c\/p\u003e\n\n\u003cp\u003eRat Gene ID: 113927\u003c\/p\u003e\n\n\u003cp\u003eRat SwissProt Number: P97633\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46313487073459,"sku":"ES4699-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46313487106227,"sku":"ES4699-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies_d75295e2-ffc1-4e0f-a3e7-87715c8983a9.jpg?v=1793190507","url":"https:\/\/afsbio.com\/products\/casein-kinase-i-%ce%b11-1l-rabbit-polyclonal-antibody-es4699","provider":"AFSBio Inc.","version":"1.0","type":"link"}